Department Background
May 12–14, 2025

Day 1

Location: BCONF & Fazıl-Say

May 12, 2025

DurationNameTopic
09:00 - 09:15Arif Ergin
Dean of the Faculty
Opening speech
Session 1 — Advisor: CEMALETTİN BEKPEN
09:15 - 09:30Aylin AkınalEvolution, Selection and Diversification of SPATA31 Genes In Human
09:30 - 09:45Çağla ÖztürkDepression as the new normal? Epigenetic inheritance, antidepressant effect, and the evolution of social behavior
09:45 - 10:00Maftuna NigmatovaEvolution of Baldness: Consequence of Selection or Aging-Related Effects
10:00 - 10:15Nami TorkamanBehavioral Rhythmicity, Circadian Regulation, and Neuromodulation in the Dead Leaf Mantis: A Comparative Transcriptomic Study
10:15 - 10:30Nariman TabbaraComparative Transcriptomic Analysis of Immune-Oncogenic Regulation in NF1 Associated MPNST vs PNST
30 minutesCoffee Break
Session 2 — Advisor: MERVE SEVEN BARAK
11:00 - 11:15Çağla AybarHuman Touch on Photosynthesis: Engineering Co2-Concentrating Mechanism (CCM) into C3 Crops and Its Impact on Carbohydrate Metabolism
11:15 - 11:30Mustafa Mert CengizThe Impact of External Magentic Field onChlorophyll Content, Leaf Morphology and Gene Expression in the Fragaria x ananassa
11:30 - 11:45Tuana ÖzdenGenetically Engineered Black Carrots and Plant-Derived Exosomes: A Novel Approach for Targeted Neuroinflammation Therapy
11:45 - 12:00Sarah A. A. AhmadBioacoustic Induction of Carotenoids in Microalgea: A Sustainable Approach to Metabolite Enhancement
45 minutesLunch Break
Session 3 — Advisor: DİLEK ÇEVİK
12:45 - 13:00Arcan GuzelogluTargeted Therapy For Cervical Cancer: Rgd-Modified Bmsc-Derived Exosomes Loaded With Mirna
13:00 - 13:15Basma HanbaliBreaking Resistance: A Multi-Target Therapy For Melanoma
13:15 - 13:30Dania M. A. HamadaMelanin-Based Multifunctional Nanoparticles For Targeted Dual-Modality Imaging In Early Ovarian Cancer Detection
13:30 - 13:45Zeynep KonyaThe Role Of Oncogenic Mirnas In The Pathogenesis Of Mycosis Fungoides: Regulation Of Tumor Suppressor Genes And T Lymphocyte Proliferation
13:45 - 14:00Humeyra CenikA Novel Therapy Approach With Repurposed Chlorpromazine Combined Temozolomide Against Glioblastoma Multiforme Through PI3K/AKT/MTOR And Wnt/Β-Catenin Signaling Pathway Inhibition
30 minutesCoffee Break
Session 4 — Advisor: ELİF EREN
14:30 - 14:45Burak Sertaç BakanEngineering B Cells to Counter Autoantibodies in Chronic Spontaneous Urticaria: A Novel Immunotherapeutic Approach
14:45 - 15:00Douaa JamaleddineBispecific Antibody Therapy as a Targeted Approach for Enhancing NK and CD8+ T Cell-Mediated Cell Clearance in Immunosenescence
15:00 - 15:15Zeynep CantürkTumor-derived Exosomes as Immune Modulators: Localized Checkpoint Blockade on Enhancing till Persistence
15:15 - 15:30Deniz Anıl ErtargınPrevention of Autoreactive T-cells Responsible for ALS-associated Autoimmunity Generation and Blockage of Their Migration into the CNS
15:30 - 15:45Semra SattarInvestigating the Role of Inflammation in Eye Receptors and its Contribution to Autism Spectrum Disorder through the cGAS-STING Signaling Pathway
15:45 - 16:00Ecem Naz DikenElucidating the Molecular Mechanism of Crosstalk Between Pyroptosis and Apoptosis

Day 2

May 13, 2025

DurationNameTopic
08:50 - 09:00Opening speech
Session 1 — Advisor: DİLEK ÇEVİK
09:00 - 09:15Azra DemirciogluImpact Of Heated Tobacco Products On Lung Cancer: The Role Of Pard3
09:15 - 09:30Ali KurelEpigenetic Ageing in Breast Cancer Survivors: Evaluating The Role Of Α-Ketoglutarate in Potential Reversal
09:30 - 09:45Farah Haj LatoufApc Resistance And Polymorphic Mirna Binding Sites In The Factor V Gene: Investigating Allele-Specific Mutations And Maternal Genetic Susceptibility In Severe Preeclampsia Outcomes
09:45 - 10:00Zeynep BerberogluInvestigating The Anti-Cancer Potential Of Eupatilin Extract From Artemisia Asiatica On Hepatocellular Carcinoma Cells
10:00 - 10:15Loubna AlaidarosInvestigating The Role Of Dysregulated Nad Levels On Sirt6 Function And Melanoma Progression
10:15 - 10:30Ghaida Abdurraouf Almasri BelhajRna Interference Mediated Regulation Of Sox2 And Sox17 To Restore Interferon Gamma Receptor Signaling And Enhance The Immune Response In Lung Cancer
30 minutesCoffee Break
Session 2 — Advisor: MERVE SEVEN BARAK
11:00 - 11:15Ayşe Sabiha TatlıdilUse of Arbuscular Mycorrhiza to Reduce the Spread of Fusarium Wilt Disease in Banana
11:15 - 11:30Enes VarlıThe Potential Role of Dimethyl Sulfide in Enhancing Drought Resistance in Crops
11:30 - 11:45Ege Talat SekkinExtending the Shelf Life of Solanum lycopersicum Fruit by Promoter-Engineered PMEU1 Gene
1 hrLunch Break
Session 3 — Advisor: ELİF EREN
12:45 - 13:00Noor Al Huda Abdul HadiGene Therapy as a Potential Cure for Alzheimer’s Disease: Targeting HSF1 And NEP Genes In IPSCS
13:00 - 13:15Taima’a Raed Omar AlqershiNeuroinflammation and Motor Neuron Health: Investigating IL-23 as an Integrative Target in Nusinersen Therapy for Spinal Muscular Atrophy (SMA)
13:15 - 13:30Deniz Anıl ErtargınPrevention of Autoreactive T-Cells Responsible for Als-Assocıated Autoimmunity Generation and Blockage of Their Migration into the CNS
13:30 - 13:45Aridj Rofaida Mohamed HadjTargeting Regulatory T Cells To Restore Immune Tolerance In Autoimmune Diseases: A Focus On Multiple Sclerosis And Type 1 Diabetes
13:45 - 14:00Ayat AlzubairiThe Role of Gut Microbiota to Regulate Tregs: Engineering Butyrate-Producing Bacterial Strains to Restore T-Regulatory Function in Multiple Sclerosis
14:00 - 14:15Reem ZinounDoes Gut Microbiota Dysbiosis Cause or Consequence of Multiple Sclerosis?
30 minutesCoffee Break
Session 4 — Advisor: CEMALETTİN BEKPEN
14:45 - 15:00Parya ZahmetkeshanSenolytic CAR-T Cells Targeting Senescent Microglia for Neurodegenerative Disease Therapy
15:00 - 15:15Asu Tuna DeligözThe Link Between Cesarean Delivery and Alzheimer’s Risk: The Role of Faecalibacterium Prausnitzii
15:15 - 15:30Buse Nur YazarFoxa2-Mediated Control of G6pc2 Expression: Regulation of Β-Cell Glucose Metabolism in Aging And Hypoglycemia Susceptibility
15:30 - 15:45Rayya El FahranUtilization of Gene Editing Strategies to Prevent Alzheimer’s Disease
15:45 - 16:00Gülru Nur AçıkgözBlood-Brain Barrier and Alzheimer Disease

Day 3

May 14, 2025

DurationNameTopic
08:50 - 09:00Opening speech
Session 1 — Advisor: CEMALETTİN BEKPEN
09:00 - 09:15Zümrütnaz AvcıTargeting Genomic Instability in Aging: Amygdalin’s and Hydroxocobalamin’s Role to Mitigate Cellular Toxicity
09:15 - 09:30Nilsu CoşkunCellular Memory and Aging; a new approach by using Methylene Blue
09:30 - 09:45Ceren VuralEarth’s electromagnetic field vs. Human body: one fundamental force to another
Session 2 — Advisor: ELİF EREN
09:45 - 10:00Hafsa BasraogluThe Future of Neurodegenerative Disease Treatments: MicroRNAs as Biomarkers of Neuronal Cell Death Guiding Personalized Medicine and Gene Therapy
10:00 - 10:15Leyla Gece ÖzcanInflammatory Cell Death Regulation in Neurodegenerative Diseases
10:15 - 10:30Shahed TürkThe Role of PANNEXIN-1 In NLRP3-Driven Inflammation and Chemoresistance in Triple- Negative Breast Cancer
30 minutesCoffee Break
Session 3 — Advisor: MERVE SEVEN BARAK
11:00 - 11:15Genco BayhanDevelopment of Molecular Markers For Early Detection of PVY-Resistant Individuals
11:15 - 11:30Alican MakçaCan RNA vaccines specifically designed against Citrus tristeza virus (CTV) trigger antiviral defense mechanisms in Citrus plants, reduce viral replication, and prevent yield loss?
11:30 - 11:45Berfin Ece ÖzandaçEvolution of ABA Responsive Genes in Aquatic versus Terrestrial Monocots: Diving Deeper into Early Land Adaptations
1 hrLunch Break
Session 4 — Advisor: DİLEK ÇEVİK
12:45 - 13:00Ece TekgeldiDetection of Early-Stage Endometrial Cancer By Using Methylation-Based Assay With Circulating Tumor Dna 'Ctdna' Methylation Patterns
13:00 - 13:15Ecem NamikkemalogluCar-Neutrophils Targeting Chronic Myeloid Leukemia Cells In The Bone Marrow To Achieve Long-Term Remission
13:15 - 13:30Emir ErenThe Mc1r R160w Variant Increases The Risk Of Prostate Cancer By Disrupting Dna Repair Mechanisms
30 minutesCoffee Break
Session 5 — Advisor: CEMALETTİN BEKPEN
14:00 - 14:15Yaren AdayDoes Gut Microbiota Dysbiosis Cause or Consequence of Multiple Sclerosis?
14:15 - 14:30Aysel Yade YılmazSenolytic CAR-T Cells Targeting Senescent Microglia for Neurodegenerative Disease Therapy
14:30 - 14:45Gülgün Ece BilalThe Link Between Cesarean Delivery and Alzheimer’s Risk: The Role of Faecalibacterium Prausnitzii
14:45 - 15:00Ayşe Ece KaramahmutFoxa2-Mediated Control of G6pc2 Expression: Regulation of Β-Cell Glucose Metabolism in Aging And Hypoglycemia Susceptibility
15:00 - 15:15Cemile Nur YıldızLMNA p.L530p In Ebv Infection and Cellular Aging
15:15 - 15:30Closing Remarks and Best Project Awards