Capstone

Project  Presentations May 2025

Projects Presentation Program 2025

May 12 2025

Location : BCONF
DurationName Topic
09:00- 09:15Arif Ergin
Dean of the Faculty
Opening speech
Session 1Advisor: CEMALETTİN BEKPEN
09:15- 09:30 Aylin AkınalEvolution, Selection and Diversification of SPATA31 Genes In Human
09:30- 09:45Çağla ÖztürkDepression as the new normal? Epigenetic inheritance, antidepressant effect, and the evolution of social behavior
09:45- 10:00Maftuna Nigmatova Evolution of Baldness: Consequence of Selection or Aging-Related Effects
10:00- 10:15Nami TorkamanBehavioral Rhythmicity, Circadian Regulation, and Neuromodulation in the Dead Leaf Mantis: A Comparative Transcriptomic Study
10:15- 10:30Nariman Tabbara Comparative Transcriptomic Analysis of Immune-Oncogenic Regulation in NF1 Associated MPNST vs PNST
30 minutesCoffee Break
Session 2Advisor: MERVE SEVEN BARAK
11:00- 11:15Çağla Aybar Human Touch on Photosynthesis: Engineering Co2-Concentrating Mechanism (CCM) into C3 Crops and Its Impact on Carbohydrate Metabolism
11:15- 11:30Mustafa Mert CengizThe Impact of External Magentic Field onChlorophyll Content, Leaf Morphology and Gene Expression in the Fragaria x ananassa
11:30- 11:45Tuana ÖzdenGenetically Engineered Black Carrots and Plant-Derived Exosomes: A Novel Approach for Targeted Neuroinflammation Therapy
11:45- 12:00Sarah A. A. AhmadBioacoustic Induction of Carotenoids in Microalgea: A Sustainable Approach to Metabolite Enhancement
45 minutesLunch Break
Session 3Advisor: DİLEK ÇEVİK
12:45- 13:00Arcan Guzeloglu Targeted Therapy For Cervical Cancer: Rgd-Modified Bmsc-Derived Exosomes Loaded With Mirna
13:00- 13:15 Basma Hanbali Breaking Resistance: A Multi-Target Therapy For Melanoma
13:15- 13:30 Dania M. A. Hamada Melanin-Based Multifunctional Nanoparticles For Targeted Dual-Modality Imaging In Early Ovarian Cancer Detection
13:30- 13:45Zeynep Konya The Role Of Oncogenic Mirnas In The Pathogenesis Of Mycosis Fungoides: Regulation Of Tumor Suppressor Genes And T Lymphocyte Proliferation
13:45- 14:00Humeyra Cenik A Novel Therapy Approach With Repurposed Chlorpromazine Combined Temozolomide Against Glioblastoma Multiforme Through PI3K/AKT/MTOR And Wnt/Β-Catenin Signaling Pathway Inhibition
30 minutesCoffee Break
Session 4Advisor: ELİF EREN
14:30 - 14:45Burak Sertaç Bakan Engineering B Cells to Counter Autoantibodies in Chronic Spontaneous Urticaria: A Novel Immunotherapeutic Approach
14:45 - 15:00Douaa JamaleddineBispecific Antibody Therapy as a Targeted Approach for Enhancing NK and CD8+ T Cell-Mediated Cell Clearance in Immunosenescence
15:00 - 15:15Zeynep Cantürk Tumor-derived Exosomes as Immune Modulators: Localized Checkpoint Blockade on Enhancing till Persistence
15:15 - 15:30Ruqayah Aymen Tawfeeq Alwatari  Impact of Stress on the Immune System Following Vaccination
15:30 - 15:45Semra Sattar Investigating the Role of Inflammation in Eye Receptors and its Contribution to Autism Spectrum Disorder through the cGAS-STING Signaling Pathway
15:45 - 16:00Ecem Naz Diken Elucidating the Molecular Mechanism of Crosstalk Between Pyroptosis and Apoptosis

May 13 2025

Location : BCONF
DurationName Topic
08:50- 09:00Opening speech
Session 1Advisor: DİLEK ÇEVİK
09:00- 09:15Azra Demircioglu Impact Of Heated Tobacco Products On Lung Cancer: The Role Of Pard3
09:15- 09:30Ali Kurel Epigenetic Ageing in Breast Cancer Survivors: Evaluating The Role Of Α-Ketoglutarate in Potential Reversal
09:30- 09:45Farah Haj Latouf Apc Resistance And Polymorphic Mirna Binding Sites In The Factor V Gene: Investigating Allele-Specific Mutations And Maternal Genetic Susceptibility In Severe Preeclampsia Outcomes
09:45- 10:00Zeynep BerberogluInvestigating The Anti-Cancer Potential Of Eupatilin Extract From Artemisia Asiatica On Hepatocellular Carcinoma Cells
10:00- 10:15Loubna Alaidaros Investigating The Role Of Dysregulated Nad Levels On Sirt6 Function And Melanoma Progression
10:15- 10:30Ghaida Abdurraouf Almasri Belhaj Rna Interference Mediated Regulation Of Sox2 And Sox17 To Restore Interferon Gamma Receptor Signaling And Enhance The Immune Response In Lung Cancer
30 minutesCoffee Break
Session 2Advisor: MERVE SEVEN BARAK
11:00- 11:15Ayşe Sabiha Tatlıdil Use of Arbuscular Mycorrhiza to Reduce the Spread of Fusarium Wilt Disease in Banana
11:15- 11:30Enes VarlıThe Potential Role of Dimethyl Sulfide in Enhancing Drought Resistance in Crops
11:30- 11:45Ege Talat SekkinExtending the Shelf Life of Solanum lycopersicum Fruit by Promoter-Engineered PMEU1 Gene
11:45- 12:00Ayşegül YavuzHeavy Metal Phycoremediation in the Marine Environments by Using Genetically Modified Gephyrocapsa huxleyi
45 minutesLunch Break
Session 3Advisor: ELİF EREN
12:45- 13:00Noor Al Huda Abdul Hadi Gene Therapy as a Potential Cure for Alzheimer’s Disease: Targeting HSF1 And NEP Genes In IPSCS
13:00- 13:15 Taima’a Raed Omar Alqershi Neuroinflammation and Motor Neuron Health: Investigating IL-23 as an Integrative Target in Nusinersen Therapy for Spinal Muscular Atrophy (SMA)
13:15- 13:30 Deniz Anıl ErtargınPrevention of Autoreactive T-Cells Responsible for Als-Assocıated Autoimmunity Generation and Blockage of Their Migration into the CNS
13:30- 13:45Aridj Rofaida Mohamed HadjTargeting Regulatory T Cells To Restore Immune Tolerance In Autoimmune Diseases: A Focus On Multiple Sclerosis And Type 1 Diabetes
13:45- 14:00Ayat Alzubairi The Role of Gut Microbiota to Regulate Tregs: Engineering Butyrate-Producing Bacterial Strains to Restore T-Regulatory Function in Multiple Sclerosis
14:00- 14:15Reem ZinounDoes Gut Microbiota Dysbiosis Cause or Consequence of Multiple Sclerosis?
30 minutesCoffee Break
Session 4Advisor: CEMALETTİN BEKPEN
14:45 - 15:00Parya Zahmetkeshan Senolytic CAR-T Cells Targeting Senescent Microglia for Neurodegenerative Disease Therapy
15:00 - 15:15Asu Tuna DeligözThe Link Between Cesarean Delivery and Alzheimer’s Risk: The Role of Faecalibacterium Prausnitzii
15:15 - 15:30Buse Nur Yazar Foxa2-Mediated Control of G6pc2 Expression: Regulation of Β-Cell Glucose Metabolism in Aging And Hypoglycemia Susceptibility
15:30 - 15:45Rayya El Fahran Utilization of Gene Editing Strategies to Prevent Alzheimer’s Disease
15:45 - 16:00Gülru Nur Açıkgöz Blood-Brain Barrier and Alzheimer Disease

May 14 2025

Location : Fazıl-Say
DurationName Topic
08:50- 09:00Opening speech
Session 1Advisor: CEMALETTİN BEKPEN
09:00- 09:15Zümrütnaz Avcı Targeting Genomic Instability in Aging: Amygdalin’s and Hydroxocobalamin’s Role to Mitigate Cellular Toxicity
09:15- 09:30Nilsu Coşkun Cellular Memory and Aging; a new approach by using Methylene Blue
09:30- 09:45Ceren Vural Earth’s electromagnetic field vs. Human body: one fundamental force to another
Session 2Advisor: ELİF EREN
09:45- 10:00Hafsa BasraogluThe Future of Neurodegenerative Disease Treatments: MicroRNAs as Biomarkers of Neuronal Cell Death Guiding Personalized Medicine and Gene Therapy
10:00- 10:15Leyla Gece Özcan Inflammatory Cell Death Regulation in Neurodegenerative Diseases
10:15- 10:30Shahed Türk The Role of PANNEXIN-1 In NLRP3-Driven Inflammation and Chemoresistance in Triple- Negative Breast Cancer
30 minutesCoffee Break
Session 3Advisor: MERVE SEVEN BARAK
11:00- 11:15Genco Bayhan Development of Molecular Markers For Early Detection of PVY-Resistant Individuals
11:15- 11:30Alican MakçaCan RNA vaccines specifically designed against Citrus tristeza virus (CTV) trigger antiviral defense mechanisms in Citrus plants, reduce viral replication, and prevent yield loss?
11:30- 11:45Berfin Ece ÖzandaçEvolution of ABA Responsive Genes in Aquatic versus Terrestrial Monocots: Diving Deeper into Early Land Adaptations
1hrLunch Break
Session 4Advisor: DİLEK ÇEVİK
12:45- 13:00Ece Tekgeldi Detection of Early-Stage Endometrial Cancer By Using Methylation-Based Assay With Circulating Tumor Dna 'Ctdna' Methylation Patterns
13:00- 13:15 Ecem Namikkemaloglu Car-Neutrophils Targeting Chronic Myeloid Leukemia Cells In The Bone Marrow To Achieve Long-Term Remission
13:15- 13:30 Emir ErenThe Mc1r R160w Variant Increases The Risk Of Prostate Cancer By Disrupting Dna Repair Mechanisms
30 minutesCoffee Break
Session 5Advisor: CEMALETTİN BEKPEN
14:00- 14:15Yaren AdayDoes Gut Microbiota Dysbiosis Cause or Consequence of Multiple Sclerosis?
14:15- 14:30Aysel Yade Yılmaz Investigating Alternative Reprogramming Strategies: The Potential of Sox1 and Krr1 in Stem Cell Regeneration
14:30 - 14:45Gülgün Ece BilalThe Role of Dnmt3a and Tet1 Methylation Patterns In Early-Life Emotional Trauma And Epigenetic Aging
14:45 - 15:00Ayşe Ece Karamahmut Drd4 And Cognitive Traits Shape Sexual Selection in Ravens (Corvus Corax)
15:00 - 15:15Cemile Nur Yıldız LMNA p.L530p In Ebv Infection and Cellular Aging
15:15 - 15:30Closing Remarks and Best Project Awards
Previous Project Presentations

Please refer to the links below for previous years project titles

Presentation Style:

For practical reason we have decided to reduce the timing for presentations. You should present your project within 10 minutes and 5 minutes for questions. This will be strictly applied. Meaning that the supervisor will stop the presentation if the timing exceed. Please be careful and practice to get the timing of presentation exact. 

Evaluation

Evaluations of the Seminar Presentations; Each advisor independently will evaluate seminar presentations from each students in a scale of :

  1. Very Good
  2. Good
  3. Sufficient
  4. Weak
  5. Very Weak
Criteria

The criteria for evaluation will be used as follows;

PRESENTATİON

  • General flow, organization, use of time
  • Control on the subject/Level of knowledge
  • Visual quality of the presentation
  • Contact with the audience
  • Language quality-Elocution
  • Answers to the questions

CONTENT

  • Introduction; Expression of the project aims
  • Body; The extent of knowledge and clarity
  • Conclusion
  • Transition among different subjects
Awards

Each Advisor will nominate three students' names, whom their pictures/details will also be included in the Capstone student webpage, for selections of Best Project Presentation Awards. At the end of the seminar presentations, advisors and each student who has presented their project will vote online from the list of 12 nominated students for the Best Project Presentation Award. This year we also include additional awards for the capstone projects. The jury will select the best project (one student) by using scientific criteria and be awarded the Best Project Award.